Hi Joe, welcome to the forum. This will really depend on the required settings from the device. Start by setting the baud rate and selecting your serial port. Then I would use the test tools to read some of the registers to determine which ones you want and that communication is working. Next add data points and set your polling rate and enable the data source and data points. You should then be able to see the data updating on the Watch List.
Here is a helpful article: https://help.infiniteautomation.com/configuring-data-sources-and-data-points/